188Re-SSS/Lipiodol: Development of a Potential Treatment for HCC from Bench to Bedside

نویسندگان

  • Nicolas Lepareur
  • Valérie Ardisson
  • Nicolas Noiret
  • Etienne Garin
چکیده

Hepatocellular carcinoma (HCC) is the 5th most common tumour worldwide and has a dark prognosis. For nonoperable cases, metabolic radiotherapy with Lipiodol labelled with β-emitters is a promising therapeutic option. The Comprehensive Cancer Centre Eugène Marquis and the National Graduate School of Chemistry of Rennes (ENSCR) have jointly developed a stable and efficient labelling of Lipiodol with rhenium-188 (E(βmax) = 2.1 MeV) for the treatment of HCC. The major "milestones" of this development, from the first syntheses to the recent first injection in man, are described.

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Re-SSS/Lipiodol: Development of a Potential Treatment for HCC from Bench to Bedside

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عنوان ژورنال:

دوره 2012  شماره 

صفحات  -

تاریخ انتشار 2012